Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 9/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661954 | 0.92 | KMT2A (0.48) | KMT2ATOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL9662874 | 0.91 | KMT2A (0.47) | KMT2ATOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL9479167 | 0.91 | KMT2A (0.47) | KMT2ATOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL10914315 | 0.90 | TOP1 (0.42) | KMT2ATOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL10894425 | 0.90 | TOP1 (0.51) | KMT2ATOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL9023293 | 0.88 | KMT2A (0.51) | KMT2ATOP2ATOP2BTOP1KCNH2 | |
| SCHEMBL9870058 | 0.88 | KMT2A (0.51) | KMT2ATOP2ATOP2BTOP1KDM4E | |
| SCHEMBL10897095 | 0.87 | KDM4E (0.55) | TOP2ATOP2BTOP1KCNH2KDM4E | |
| SCHEMBL10663128 | 0.87 | TOP1 (0.55) | KMT2ATOP1KDM4EALDH1A1HPGD | |
| SCHEMBL10553439 | 0.87 | KDM4E (0.45) | KMT2ATOP2ATOP2BTOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |