Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10249607 | 0.87 | OGG1 (0.51) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL13219092 | 0.85 | OGG1 (0.54) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL13540951 | 0.85 | OGG1 (0.54) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL19405290 | 0.84 | OGG1 (0.49) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL17164015 | 0.82 | OGG1 (0.51) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL11611713 | 0.82 | OGG1 (0.48) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL19513376 | 0.82 | SLC6A4 (0.57) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL19513375 | 0.82 | SLC6A4 (0.57) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL105734 | 0.82 | OGG1 (0.57) | OGG1SLC6A4KMT2AGRM5L3MBTL1 | |
| SCHEMBL11515179 | 0.81 | OGG1 (0.47) | OGG1SLC6A4KMT2AGRM5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |