Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389722 | 0.86 | MAPT (0.46) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL9383425 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAMAPTPOLB | |
| SCHEMBL9385515 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAMAPTPOLB | |
| Oxalic Acid SCHEMBL9384490 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAMAPTPOLB | |
| Oxalic Acid SCHEMBL9388883 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAMAPTPOLB | |
| SCHEMBL9388550 | 0.78 | PDE4B (0.46) | ALDH1A1LMNAGAAMAPTPOLB | |
| SCHEMBL9385211 | 0.76 | MAPT (0.50) | ALDH1A1LMNAMAPTPOLBPKM | |
| SCHEMBL9384217 | 0.76 | CDK2 (0.53) | ALDH1A1LMNAGAAMAPTPKM | |
| SCHEMBL9384185 | 0.76 | MAPT (0.51) | ALDH1A1LMNAGAAMAPTPKM | |
| SCHEMBL9383379 | 0.75 | PDE4B (0.46) | ALDH1A1LMNAMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |