SCHEMBL9870201

SCHEMBL9870201

[c]1nc(-c2cc3ccccc3[c]n2)cc2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ACHE P22303 1/20 0.35
CYP2A6 P11509 1/20 0.33
ALOX12 P18054 1/20 0.33
NQO2 P16083 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
NPC1 O15118 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL637345 0.87 MEN1 (0.43) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL5595305 0.86 KDM4E (0.52) ALDH1A1GLAMAPTHPGDNPC1
SCHEMBL78634 0.84 RAB9A (0.44) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL6247283 0.84 KDM4E (0.41) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL115772 0.83 NPC1 (0.34) ALDH1A1MAPTNPC1KDM4E
SCHEMBL17048404 0.83
SCHEMBL6773803 0.83 NTRK1 (0.30)
SCHEMBL2187573 0.80 MEN1 (0.43) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL1879034 0.79 PDPK1 (0.43) ALDH1A1GLAMAPTHPGDACHE
SCHEMBL9479758 0.79 MIF (0.31) ALDH1A1GLAMAPTHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006660-A Reacting a halogenbenzene with alcohol or phenol in presence od copper(or compound thereof), amine, and base FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed