SCHEMBL987049

SCHEMBL987049

Cc1cnc(N2CCC(Oc3ncnc(Nc4ccc(S(C)(=O)=O)cc4F)c3C)CC2)cn1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.67
CYP2C9 P11712 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1890870 0.82 GPR119 (0.69) GPR119
SCHEMBL6368465 0.82 GPR119 (0.67) GPR119CYP2C9
SCHEMBL390965 0.80 GPR119 (0.68) GPR119CYP2C9
SCHEMBL389148 0.80 GPR119 (0.75) GPR119CYP2C9
SCHEMBL388998 0.80 GPR119 (1.00) GPR119CYP2C9
SCHEMBL2401451 0.80 GPR119 (0.65) GPR119CYP2C9
SCHEMBL5187894 0.80 GPR119 (0.70) GPR119CYP2C9
SCHEMBL2405518 0.80 GPR119 (0.65) GPR119CYP2C9
SCHEMBL389010 0.80 GPR119 (0.79) GPR119CYP2C9
SCHEMBL389611 0.79 GPR119 (0.73) GPR119CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011005929-A1 PIPERIDINE DERIVATIVE AND ITS USE FOR THE TREATMENT OF DIABETS AND OBESITY ARENA PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2011005929-A1 PIPERIDINE DERIVATIVE AND ITS USE FOR THE TREATMENT OF DIABETS AND OBESITY ARENA PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed