Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870531 | 1.00 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9870535 | 1.00 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10528727 | 0.88 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9869914 | 0.88 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9869917 | 0.88 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313807 | 0.84 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313794 | 0.84 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9313797 | 0.84 | ABCC9 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7320898 | 0.83 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7320895 | 0.83 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043344-A | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |