Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9591326 | 0.89 | — | — | |
| SCHEMBL9869892 | 0.68 | — | — | |
| SCHEMBL11016888 | 0.67 | — | — | |
| SCHEMBL28119509 | 0.64 | TSHR (0.48) | — | |
| SCHEMBL4901963 | 0.64 | — | — | |
| SCHEMBL1752773 | 0.64 | KMT2A (0.44) | — | |
| SCHEMBL27372085 | 0.62 | TSHR (0.46) | — | |
| SCHEMBL1564826 | 0.61 | HDAC8 (0.43) | HDAC8 | |
| SCHEMBL30637701 | 0.61 | HDAC8 (0.44) | HDAC8 | |
| SCHEMBL1717839 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049558-A | Quaternized nitrogen-heterocycle substituted | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |
| EP-0164944-B1 | CEPHALOSPORIN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-11 | — | — | EP | disclosed |
| EP-0164944-A1 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-18 | — | — | EP | disclosed |