SCHEMBL9869892

SCHEMBL9869892

C[n+]1nc(Cl)ccc1Cl.F[B-](F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11016888 0.81
SCHEMBL9870567 0.68 HDAC8 (0.34)
SCHEMBL13203263 0.62
SCHEMBL1754620 0.62
SCHEMBL9593568 0.58
SCHEMBL34461983 0.57 ACHE (0.44)
SCHEMBL28119509 0.56 TSHR (0.48)
SCHEMBL28079002 0.55 KEAP1 (0.36)
SCHEMBL6863235 0.55 LMNA (0.32)
SCHEMBL27372085 0.54 TSHR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564636-B2 Pnictogen-containing heterocyclic compounds and their use UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2026-03-03 US disclosed
US-20240285772-A1 PNICTOGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE COLGATE UNIVERSITY 2024-08-29 US disclosed
WO-2023191953-A1 PNICTOGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) 2023-10-05 WO disclosed
US-5049558-A Quaternized nitrogen-heterocycle substituted IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-17 US disclosed
EP-0164944-B1 CEPHALOSPORIN DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-07-11 EP disclosed
EP-0164944-A1 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-12-18 EP disclosed