Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473682 | 0.91 | DRD2 (0.54) | KMT2ADRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7225414 | 0.90 | DRD2 (0.52) | KMT2ADRD2HTR2AHTR2CHTR2B | |
| SCHEMBL13122649 | 0.85 | KMT2A (0.74) | KMT2AKHKCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3444508 | 0.85 | KMT2A (0.74) | KMT2AKHKCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3444511 | 0.85 | KMT2A (0.74) | KMT2AKHKCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6611458 | 0.82 | DRD2 (0.65) | KMT2ADRD2HTR2AHTR2CHTR2B | |
| SCHEMBL948505 | 0.81 | DRD2 (0.60) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14784803 | 0.81 | DRD2 (0.63) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL11098055 | 0.80 | DRD2 (0.58) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL5469826 | 0.79 | DRD2 (0.73) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077288-A | Adrenergic, serotonin and histamine antagonist | ADIR ET COMPAGNIE (FR) | 1991-12-31 | — | — | US | disclosed |
| US-3962257-A | 3-PHENACYLPIPERIDINES | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |