Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 11/20 | 0.53 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134658 | 0.87 | DYRK1A (0.60) | WNT3APORCNDYRK1APSEN1PSEN2 | |
| SCHEMBL30559511 | 0.87 | DYRK1A (0.60) | WNT3APORCNDYRK1APSEN1PSEN2 | |
| Iodide SCHEMBL28741643 | 0.85 | DYRK1A (0.58) | WNT3APORCNDYRK1APSEN1PSEN2 | |
| SCHEMBL8383748 | 0.83 | DYRK1A (0.56) | WNT3APORCNDYRK1APSEN1PSEN2 | |
| SCHEMBL17517234 | 0.79 | DYRK1A (0.53) | WNT3APORCNDYRK1APSEN1PSEN2 | |
| SCHEMBL17517235 | 0.78 | DYRK1A (0.51) | WNT3APORCNDYRK1APSEN1PSEN2 | |
| Biphenyl SCHEMBL20583591 | 0.77 | ALDH1A1 (0.53) | — | |
| SCHEMBL30308690 | 0.77 | DYRK1A (0.65) | WNT3ADYRK1APSEN1PSEN2APH1B | |
| SCHEMBL1896511 | 0.77 | DYRK1A (0.65) | WNT3ADYRK1APSEN1PSEN2APH1B | |
| SCHEMBL16675759 | 0.76 | PRKCI (0.64) | WNT3ADYRK1APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997837-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4906624-A | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0306929-A2 | 6-[[(Substituted)pyridin-3-YL]alkyl]-and alkenyl]-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |