Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872209 | 1.00 | EPHX2 (0.58) | EPHX2ALDH1A1L3MBTL1TDP1FAAH | |
| SCHEMBL839310 | 1.00 | EPHX2 (0.58) | EPHX2ALDH1A1L3MBTL1TDP1FAAH | |
| SCHEMBL2638931 | 1.00 | EPHX2 (0.58) | EPHX2ALDH1A1L3MBTL1TDP1FAAH | |
| SCHEMBL8984483 | 1.00 | EPHX2 (0.58) | EPHX2ALDH1A1L3MBTL1TDP1FAAH | |
| SCHEMBL2070766 | 0.98 | EPHX2 (0.56) | EPHX2ALDH1A1L3MBTL1TDP1FAAH | |
| SCHEMBL3603037 | 0.93 | ALDH1A1 (0.52) | EPHX2ALDH1A1L3MBTL1TDP1FAAH | |
| SCHEMBL29025335 | 0.88 | EPHX2 (0.48) | EPHX2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL25269510 | 0.86 | EPHX2 (0.57) | EPHX2L3MBTL1TDP1FAAHTSHR | |
| SCHEMBL2871485 | 0.86 | MAPT (0.59) | EPHX2L3MBTL1TDP1FAAHTSHR | |
| SCHEMBL1007119 | 0.86 | MAPT (0.59) | EPHX2L3MBTL1TDP1FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070139-A | PLATELET ACTIVATING FACTOR ANTAGONISTS, HYPOTENSIVES | J. URIACH & CIA. S.A. (ES) | 1991-12-03 | — | — | US | disclosed |
| US-4940706-A | 2,4-disubstituted 1,3-dioxolanes and pharmaceutical use | J. URIACH & CIA, S.A. (ES) | 1990-07-10 | — | — | US | disclosed |
| EP-0312041-A2 | 2,4-Disubstituted 1,3-dioxolanes | J. URIACH & CIA. S.A. (ES) | 1989-04-19 | — | — | EP | disclosed |