Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283521 | 1.00 | CYP1A2 (0.40) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL6118705 | 0.85 | GAA (0.44) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL10773024 | 0.82 | TSHR (0.46) | GAAL3MBTL1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL5497077 | 0.81 | TSHR (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL14523084 | 0.81 | TSHR (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL1258369 | 0.78 | GAA (0.55) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL12925787 | 0.78 | GAA (0.41) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL28172951 | 0.78 | GAA (0.41) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL15153932 | 0.77 | L3MBTL1 (0.49) | CYP1A2MGAMGAASIMGAM2 | |
| SCHEMBL2912543 | 0.77 | MGAM (0.44) | CYP1A2MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772052-A | Medical intermediate and preparation method thereof | 湖南九维生物医药有限公司 | 2024-10-15 | — | — | CN | disclosed |
| US-4997837-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4957940-A | ENZYME INHIBITORS, ANTILIPEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-09-18 | — | — | US | disclosed |
| US-4950675-A | ANTICHOLESTEROL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-08-21 | — | — | US | disclosed |
| US-4929620-A | ANTILIPEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4906624-A | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4906657-A | Bicyclo heptane and bicyclo octane substituted inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4868185-A | HYPOLIPIDEMIC, ANTICHOLESTEROL | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0306929-A2 | 6-[[(Substituted)pyridin-3-YL]alkyl]-and alkenyl]-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4761419-A | ANTILIPEMIC | WARNER-LAMBERT COMPANY (US) | 1988-08-02 | — | — | US | disclosed |
| US-4650890-A | Preparation of olefinic compounds and intermediates thereof | SANDOZ CORP. (US) | 1987-03-17 | — | — | US | disclosed |