Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870176 | 0.89 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM4CYP1A2 | |
| SCHEMBL9871211 | 0.89 | CHRM2 (0.59) | CHRM2CHRM1CHRM3CHRM4CYP1A2 | |
| SCHEMBL9870460 | 0.89 | CHRM2 (0.59) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9870956 | 0.88 | CHRM2 (0.58) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL10514497 | 0.83 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL10506912 | 0.82 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM4CYP1A2 | |
| SCHEMBL10516278 | 0.81 | CHRM2 (0.59) | CHRM2CHRM1CHRM3CHRM4CYP1A2 | |
| SCHEMBL10515306 | 0.80 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9870103 | 0.79 | CHRM2 (0.54) | CHRM2CHRM1CHRM3CHRM4CYP1A2 | |
| SCHEMBL10507523 | 0.79 | CHRM2 (0.75) | CHRM2CHRM1CHRM3CHRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002943-A | Antispasmodic Agents, Bradycardia Treatment | MIHM GERHARD (DE) | 1991-03-26 | — | — | US | disclosed |