Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871184 | 1.00 | ABCC9 (0.42) | ABCC9HTR6TP53RXFP1FEN1 | |
| SCHEMBL9871178 | 1.00 | ABCC9 (0.42) | ABCC9HTR6TP53RXFP1FEN1 | |
| SCHEMBL9870395 | 0.84 | ABCC9 (0.46) | ABCC9HTR6ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9870400 | 0.84 | ABCC9 (0.46) | ABCC9HTR6ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9870410 | 0.84 | ABCC9 (0.46) | ABCC9HTR6ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9293694 | 0.83 | ABCC9 (0.50) | ABCC9HTR6TP53RXFP1ABCC8 | |
| SCHEMBL9293698 | 0.83 | ABCC9 (0.50) | ABCC9HTR6TP53RXFP1ABCC8 | |
| SCHEMBL9293691 | 0.83 | ABCC9 (0.50) | ABCC9HTR6TP53RXFP1ABCC8 | |
| SCHEMBL9293382 | 0.83 | ABCC9 (0.52) | ABCC9HTR6TP53RXFP1FEN1 | |
| SCHEMBL9294111 | 0.83 | ABCC9 (0.52) | ABCC9HTR6TP53RXFP1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043344-A | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0337179-A1 | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-18 | — | — | EP | disclosed |