SCHEMBL9871206

SCHEMBL9871206

CCCCc1nc2c(N)nnc(N)c2n1Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 4/20 0.66
AGTR1 P30556 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9872755 0.86 AGTR2 (0.67) AGTR2AGTR1
SCHEMBL9874239 0.86 AGTR2 (0.67) AGTR2AGTR1
SCHEMBL9873893 0.86 AGTR2 (0.71) AGTR2AGTR1
SCHEMBL9871891 0.85 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL9873381 0.85 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL9873151 0.85 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL9874860 0.85 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL9873003 0.84 AGTR2 (0.65) AGTR2AGTR1
SCHEMBL9872750 0.84 AGTR2 (0.65) AGTR2AGTR1
SCHEMBL9871654 0.84 AGTR2 (0.65) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991019715-A1 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS G.D. SEARLE & CO. (US) 1991-12-26 WO disclosed