Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987059 | 0.91 | GAA (0.38) | GAAHTTL3MBTL1 | |
| SCHEMBL2864052 | 0.88 | TSHR (0.46) | GAAHTTTSHRKMT2AALDH1A1 | |
| Acetic Acid SCHEMBL988128 | 0.87 | TSHR (0.35) | GAATSHRKMT2ATAAR1ALDH1A1 | |
| Acetic Acid SCHEMBL27931191 | 0.82 | GAA (0.33) | GAAHTT | |
| SCHEMBL15672481 | 0.82 | GAA (0.41) | GAAHTTL3MBTL1 | |
| SCHEMBL2218799 | 0.81 | GAA (0.35) | GAAHTTL3MBTL1 | |
| SCHEMBL987130 | 0.80 | TSHR (0.50) | GAATSHRKMT2AALDH1A1ESR1 | |
| SCHEMBL14648316 | 0.79 | GBA1 (0.39) | GAAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL15672512 | 0.78 | GAA (0.39) | GAAHTTL3MBTL1KDM4E | |
| SCHEMBL16790813 | 0.78 | GAA (0.39) | GAAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9358195-B2 | Stabilized body care products, household products, textiles and fabrics | BASF SE (DE) | 2016-06-07 | — | — | US | claimed |
| EP-2464739-B1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2016-01-13 | — | — | EP | claimed |
| US-8859235-B2 | Methods in cell cultures, and related inventions, employing certain additives | BASF SE (DE) | 2014-10-14 | — | — | US | claimed |
| US-20140287250-A1 | COLOR STABILIZATION OF CORK AND COLORED WOODS BY THE COMBINED USE OF INORGANIC AND ORGANIC UV-ABSORBERS | BASF SE (DE) | 2014-09-25 | — | — | US | claimed |
| EP-1896550-B1 | STABILIZED ELECTROCHROMIC MEDIA | BASF SE (DE) | 2013-08-14 | — | — | EP | claimed |
| US-20120328893-A1 | COLOR STABILIZATION OF CORK AND COLORED WOODS BY THE COMBINED USE OF INORGANIC AND ORGANIC UV-ABSORBERS | SCHALLER CHRISTIAN MARCUS (CH) | 2012-12-27 | — | — | US | claimed |
| EP-1680541-B1 | STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS | BASF SE (DE) | 2012-12-19 | — | — | EP | claimed |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-28 | — | — | US | claimed |
| EP-2464739-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-20 | — | — | EP | claimed |
| WO-2011018472-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2011-02-17 | — | — | WO | claimed |
| US-6653324-B1 | Impregnating with sterically hindered amine N-oxyl or N-hydroxyl; protecting against light-induced degradation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-25 | — | — | US | claimed |
| EP-1362083-A1 | INK-JET INK AND RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2003-11-19 | — | — | EP | claimed |
| EP-0943665-B1 | Stabilization of wood substrates | CIBA SC HOLDING AG (CH) | 2003-11-05 | — | — | EP | claimed |
| US-20020124980-A1 | Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives | SELTZER RAYMOND R (US) | 2002-09-12 | — | — | US | claimed |
| WO-2002055618-A1 | INK-JET INK AND RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-07-18 | — | — | WO | claimed |
| EP-1207984-A1 | STABILIZATION OF WOOD SUBSTRATES | Ciba SC Holding AG (CH) | 2002-05-29 | — | — | EP | claimed |
| US-6254724-B1 | STABILIZING AMOUNT OF A HINDERED AMINE COMPOUND SELECTED DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL OR WHICH ARE THEIR HYDROXYLAMINE SALTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-03 | — | — | US | claimed |
| WO-2001017738-A1 | STABILIZATION OF WOOD SUBSTRATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-15 | — | — | WO | claimed |
| US-6187387-B1 | PROTECTING WOOD AGAINST LIGHT-INDUCED DEGRADATION BY TREATMENT WITH STAIN OR IMPREGNATION WHICH PENETRATES SURFACE OF WOOD COMPRISING HINDETED AMINE COMPOUND AND SOLVENT | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-13 | — | — | US | claimed |
| EP-0943665-A1 | Stabilization of wood substrates | Ciba SC Holding AG (CH) | 1999-09-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BBOX1, NEFM, NQO1 | ESR1 4385/4885GAA 3210/4885HTT 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.