Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456400 | 0.99 | MEN1 (0.35) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL483589 | 0.97 | MEN1 (0.35) | MEN1THRBAPEX1RECQLBLM | |
| Ciaftalan SCHEMBL9792952 | 0.93 | MEN1 (0.38) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL813548 | 0.93 | MEN1 (0.38) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL2786994 | 0.91 | MEN1 (0.38) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL8958676 | 0.84 | HSD17B10 (0.40) | MEN1KMT2ACYP1A2CYP3A4HSD17B10 | |
| Ciaftalan SCHEMBL239995 | 0.81 | MEN1 (0.45) | MEN1THRBAPEX1RECQLBLM | |
| Ciaftalan SCHEMBL590020 | 0.81 | MEN1 (0.45) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL8414712 | 0.80 | MEN1 (0.37) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL789380 | 0.79 | MEN1 (0.39) | MEN1THRBAPEX1RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996311-A | Crystal structure, stability | COMMISSARIAT A. L'ENERGIE ATOMIQUE (FR) | 1991-02-26 | — | — | US | disclosed |