SCHEMBL3456400

SCHEMBL3456400

Cc1c(C)c(C)c2c(c1C)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1c(C)c(C)c(C)c(C)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 4/20 0.33
CYP2C19 P33261 4/20 0.33
CYP3A4 P08684 3/20 0.33
HSD17B10 Q99714 3/20 0.33
CYP2D6 P10635 2/20 0.33
CLK4 Q9HAZ1 2/20 0.33
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
KDM4E B2RXH2 3/20 0.32
TSHR P16473 3/20 0.32
TOP2A P11388 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483589 0.99 MEN1 (0.35) MEN1THRBAPEX1RECQLBLM
SCHEMBL9871307 0.99 MEN1 (0.35) MEN1THRBAPEX1RECQLBLM
SCHEMBL813548 0.94 MEN1 (0.38) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL9792952 0.94 MEN1 (0.38) MEN1THRBAPEX1RECQLBLM
SCHEMBL2786994 0.92 MEN1 (0.38) MEN1THRBAPEX1RECQLBLM
SCHEMBL8958676 0.85 HSD17B10 (0.40) MEN1KMT2ACYP1A2CYP3A4HSD17B10
SCHEMBL813083 0.80 MEN1 (0.46) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL29356273 0.80 MEN1 (0.46) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL29360952 0.80 MEN1 (0.46) MEN1THRBAPEX1RECQLBLM
Ciaftalan SCHEMBL1728179 0.80 MEN1 (0.46) MEN1THRBAPEX1RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262032-A2 Organic electroluminescence device and its manufacturing method Idemitsu Kosan Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-0661366-B1 A copolymer, a process for producing the same and an electroluminescent element using the same CHISSO CORP (JP) 2000-04-26 EP disclosed
US-5587444-A Copolymer, a process for producing the same and an electroluminescent element using the same CHISSO CORPORATION (JP) 1996-12-24 US disclosed
EP-0661366-A1 A copolymer, a process for producing the same and an electroluminescent element using the same Chisso Corporation (JP) 1995-07-05 EP disclosed
EP-0261733-B1 CONDUCTIVE POLYMER COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-01-15 EP disclosed
US-5034463-A Forming a solution of an electroconductive polymer in a solvent, a metallized polymer SHELL OIL CORPORATION (US) 1991-07-23 US disclosed
EP-0261733-A2 Conductive polymer compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-03-30 EP disclosed