Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870645 | 1.00 | CETP (0.38) | CETPHSD17B10AKR1C3MAOBPDK2 | |
| SCHEMBL9870650 | 1.00 | CETP (0.38) | CETPHSD17B10AKR1C3MAOBPDK2 | |
| SCHEMBL9871287 | 0.79 | AKR1C3 (0.42) | CETPHSD17B10AKR1C3MAOBPDK2 | |
| SCHEMBL9718914 | 0.79 | AKR1C3 (0.42) | CETPHSD17B10AKR1C3MAOBPDK2 | |
| SCHEMBL9871832 | 0.79 | AKR1C3 (0.42) | CETPHSD17B10AKR1C3MAOBPDK2 | |
| SCHEMBL4658587 | 0.71 | AKR1C3 (0.51) | HSD17B10AKR1C3MAOBHDAC3HDAC4 | |
| SCHEMBL29838830 | 0.68 | KMT2A (0.42) | MAOBHDAC6MEN1KMT2A | |
| SCHEMBL22559 | 0.67 | LTA4H (0.75) | AKR1C3MAOBHDAC8KDM4EALDH1A1 | |
| SCHEMBL30018242 | 0.67 | LTA4H (0.75) | AKR1C3MAOBHDAC8KDM4EALDH1A1 | |
| SCHEMBL1173711 | 0.67 | LTA4H (0.75) | AKR1C3MAOBHDAC8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032301-A | High performance lubricants comprising triazine derivatives | THE DOW CHEMICAL COMPANY (US) | 1991-07-16 | — | — | US | disclosed |