Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871449 | 1.00 | PREP (0.52) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9871454 | 1.00 | PREP (0.52) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9871484 | 0.93 | CAPN1 (0.54) | PREPACECTSLCTSBLMNA | |
| SCHEMBL9872158 | 0.93 | CAPN1 (0.54) | PREPACECTSLCTSBLMNA | |
| SCHEMBL10775507 | 0.93 | PREP (0.55) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10775495 | 0.93 | PREP (0.55) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10775501 | 0.93 | PREP (0.55) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14067705 | 0.91 | PREP (0.53) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8331221 | 0.90 | ACE (0.60) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20484652 | 0.90 | ACE (0.60) | PREPCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |