Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 4/20 | 0.53 |
| ▸ | CMA1 | P23946 | 4/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872158 | 1.00 | CAPN1 (0.54) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL9871460 | 0.93 | PREP (0.52) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL9871449 | 0.93 | PREP (0.52) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL9871454 | 0.93 | PREP (0.52) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL10080680 | 0.92 | ELANE (0.57) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL10063674 | 0.88 | ACE (0.61) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL1506251 | 0.88 | ACE (0.61) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL7761026 | 0.87 | CCR1 (0.55) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL22209363 | 0.86 | ALDH1A1 (0.62) | CAPN1CTSLCTSBCTSKPREP | |
| SCHEMBL30051146 | 0.86 | ALDH1A1 (0.62) | CAPN1CTSLCTSBCTSKPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |