Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRHR | P34981 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069460 | 0.88 | CDK5 (0.47) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| SCHEMBL6527840 | 0.88 | CDK5 (0.47) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| Hydrochloric Acid SCHEMBL7356305 | 0.87 | CDK5 (0.46) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| Hydrochloric Acid SCHEMBL6527838 | 0.87 | CDK5 (0.46) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| Hydrochloric Acid SCHEMBL6527843 | 0.87 | CDK5 (0.46) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| Hydrochloric Acid SCHEMBL5997862 | 0.87 | CDK5 (0.46) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| SCHEMBL289025 | 0.86 | ALPI (0.53) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| SCHEMBL4956555 | 0.86 | ALPI (0.53) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| SCHEMBL41832 | 0.86 | ALPI (0.53) | CPB2TRHDEKDM4CKDM5AKDM5B | |
| SCHEMBL5717571 | 0.85 | CPB2 (0.47) | CPB2TRHDEKDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025027-A | For stimulation of the parasympathetic system and treatment of glaucoma; improved duration | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-06-18 | — | — | US | disclosed |
| WO-1990010000-A1 | CYCLIC CARBAMATE ANALOGUES OF (+)-PILOCARPINE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-09-07 | — | — | WO | disclosed |