Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.34 |
| ▸ | MYLK | Q15746 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKCB | P05771 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKCH | P24723 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871650 | 0.75 | PRKD3 (0.40) | ADRA2AADRA2BADRA2CPRKD3PRKCG | |
| Hydrochloric Acid SCHEMBL9871784 | 0.71 | ALDH1A1 (0.33) | KCNH2CYP3A4CYP2D6 | |
| SCHEMBL9871149 | 0.70 | CYP3A4 (0.38) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL9872164 | 0.69 | METAP1 (0.39) | MYLKPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL9872690 | 0.66 | CYP3A4 (0.41) | KCNH2CYP3A4CYP1A2CYP2D6HTR3E | |
| SCHEMBL9870672 | 0.65 | HDAC1 (0.42) | KCNH2CYP3A4CYP1A2CYP2D6HTR3E | |
| SCHEMBL9873374 | 0.65 | PDGFRB (0.43) | CYP2D6HTR2B | |
| SCHEMBL9872923 | 0.65 | KCNH2 (0.40) | KCNH2CYP3A4CYP1A2CYP2D6HTR3E | |
| SCHEMBL9571779 | 0.65 | KCNH2 (0.38) | ADRA2CKCNH2CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9870845 | 0.64 | CYP3A4 (0.39) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |