Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278981 | 0.79 | — | — | |
| SCHEMBL14339554 | 0.77 | CCR5 (0.35) | CCR5CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19499460 | 0.77 | CCR5 (0.31) | CCR5 | |
| SCHEMBL13069213 | 0.74 | CA1 (0.33) | CCR5 | |
| SCHEMBL23654554 | 0.72 | CCR5 (0.31) | CCR5 | |
| SCHEMBL18781502 | 0.72 | CCR5 (0.31) | CCR5 | |
| SCHEMBL22009743 | 0.72 | CCR5 (0.31) | CCR5 | |
| SCHEMBL22009741 | 0.72 | CCR5 (0.31) | CCR5 | |
| SCHEMBL22481362 | 0.69 | — | — | |
| SCHEMBL22481438 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359172-A1 | Azabicycloalkanes | SHIONOGI & CO., LTD. (JP) | 1990-03-21 | — | — | EP | claimed |
| WO-2014043272-A1 | TRICYCLIC GYRASE INHIBITORS FOR USE AS ANTIBACTERIAL AGENTS | TRIUS THERAPEUTICS INC. (US) | 2014-03-20 | — | — | WO | disclosed |
| US-5017708-A | Azabicycloalkanes | SHIONOGI & CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0359172-A1 | Azabicycloalkanes | SHIONOGI & CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |