Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Benzylmethylamine SCHEMBL4609847 | 0.95 | CYP3A4 (0.94) | MAPTCYP3A4KDM4EIDO1THRB | |
| SCHEMBL24334039 | 0.95 | CYP3A4 (0.94) | MAPTCYP3A4KDM4EIDO1THRB | |
| N-Benzylmethylamine SCHEMBL2271 | 0.95 | — | — | |
| N-Benzylmethylamine SCHEMBL11696446 | 0.95 | CYP3A4 (0.94) | MAPTCYP3A4KDM4EIDO1THRB | |
| N-Benzylmethylamine SCHEMBL224962 | 0.92 | CYP3A4 (0.90) | MAPTCYP3A4KDM4EIDO1THRB | |
| N-Benzylmethylamine SCHEMBL837568 | 0.92 | CYP3A4 (0.90) | MAPTCYP3A4KDM4EIDO1THRB | |
| N-Benzylmethylamine SCHEMBL9346326 | 0.92 | CYP3A4 (0.90) | MAPTCYP3A4KDM4EIDO1THRB | |
| N-Benzylmethylamine SCHEMBL8083805 | 0.92 | — | — | |
| N-Benzylmethylamine SCHEMBL237384 | 0.92 | MAPT (1.00) | MAPTCYP3A4KDM4EIDO1THRB | |
| N-Benzylmethylamine SCHEMBL31281074 | 0.92 | CYP3A4 (0.90) | MAPTCYP3A4KDM4EIDO1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |
| EP-0027695-B1 | MORPHOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | JOHN WYETH & BROTHER LIMITED (GB) | 1983-10-12 | — | — | EP | disclosed |