Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAD | Q92934 | 2/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RGS17 | Q9UGC6 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403982 | 0.90 | BAD (0.49) | BADHPRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL30400843 | 0.90 | BAD (0.49) | BADHPRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL30012637 | 0.81 | BAD (0.44) | BADHPRT1ALDH1A1MAPTKDM4E | |
| SCHEMBL2029565 | 0.76 | HPRT1 (0.61) | HPRT1ALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL8231432 | 0.76 | GPR84 (0.52) | HPRT1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL3073151 | 0.75 | ITGB2 (0.46) | HPRT1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL1692303 | 0.73 | BAD (0.48) | BADALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL25510 | 0.72 | HPRT1 (1.00) | HPRT1ALDH1A1MAPTMAPK1HSD17B10 | |
| Chrysene SCHEMBL384031 | 0.72 | HPRT1 (1.00) | HPRT1ALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL31177955 | 0.72 | HPRT1 (1.00) | HPRT1ALDH1A1MAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5024743-A | Prophylaxis and therapy of infectious diseases | MADAUS GMBH & CO. (DE) | 1991-06-18 | — | — | US | disclosed |
| US-4835178-A | Methylendioxyphenathrene and stilben derivatives, process for the preparation thereof, pharmaceutical compositions using these, and therapeutic applications | DR. MADAUS & CO. (DE) | 1989-05-30 | — | — | US | disclosed |