Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112863 | 0.80 | FBP1 (0.61) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL16030559 | 0.80 | FBP1 (0.56) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL8137951 | 0.80 | FBP1 (0.61) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL4631917 | 0.80 | FBP1 (0.56) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL4631916 | 0.80 | FBP1 (0.56) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL11498501 | 0.76 | FBP1 (0.51) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL11498503 | 0.76 | FBP1 (0.51) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL21631225 | 0.72 | FBP1 (0.60) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL21631226 | 0.72 | FBP1 (0.60) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL2820854 | 0.72 | FBP1 (1.00) | FBP1PRMT1AKR1C3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997954-A | Process for preparing substituted isoindolinone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-03-05 | — | — | US | disclosed |