Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189215 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL16933840 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL10396091 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL16933737 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL10397143 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL6058462 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL10397196 | 1.00 | EP300 (0.52) | EP300TSHRTHRBFAAHTRPV1 | |
| SCHEMBL764808 | 0.97 | — | — | |
| SCHEMBL10491615 | 0.93 | FAAH (0.52) | FAAHTRPV1TERTMAPTBLM | |
| SCHEMBL10491621 | 0.93 | FAAH (0.52) | FAAHTRPV1TERTMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997855-A | Nematocides, insecticides, anthelmintics | FMC CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4876285-A | ANTHELMINTIC UTILITY | FMC CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |