Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984759 | 0.80 | MAPT (0.53) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL9062727 | 0.77 | KMT2A (0.44) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL7692195 | 0.77 | KMT2A (0.67) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL4293438 | 0.76 | KMT2A (0.65) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL4286016 | 0.76 | KMT2A (0.65) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL4304569 | 0.76 | KMT2A (0.65) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL4393540 | 0.76 | MAPT (0.49) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL4395732 | 0.76 | MAPT (0.49) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL29154092 | 0.74 | MAPT (0.46) | PIM1MAPTKDM4ELMNAHSP90AA1 | |
| SCHEMBL1507963 | 0.73 | MAPT (0.46) | PIM1MAPTKDM4ELMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891627-B | Ruthenium-containing coordination compound and preparation method thereof | CHINESE ACAD INST CHEMISTRY | 2015-04-29 | — | — | CN | claimed |
| CN-101891627-B | Ruthenium-containing coordination compound and preparation method thereof | CHINESE ACAD INST CHEMISTRY | 2015-04-29 | — | — | CN | disclosed |
| US-5032402-A | 3-hydroxy-N-methylpyrrolidone and use as transdermal enhancer | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1991-07-16 | — | — | US | disclosed |
| US-4973708-A | TRANSDERMAL ENHANCER FOR PENETRATION OF DRUGS THROUGH THE SKIN | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-11-27 | — | — | US | disclosed |