Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.36 |
| ▸ | ACACA | Q13085 | 9/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17985453 | 0.77 | HTR2C (0.41) | ACACBACACAIDO1CA12CA1 | |
| SCHEMBL17986441 | 0.76 | HTR2C (0.59) | — | |
| SCHEMBL17986442 | 0.75 | HTR2C (0.47) | CKS1BSKP1SKP2 | |
| SCHEMBL13742044 | 0.74 | ACACB (0.43) | ACACBACACAIDO1CKS1BSKP1 | |
| SCHEMBL17986332 | 0.74 | SERPINE1 (0.41) | ACACBACACACA12CA1CA2 | |
| SCHEMBL17985451 | 0.73 | HTR2A (0.43) | ACACBACACAIDO1CA12CA1 | |
| SCHEMBL17985454 | 0.73 | HTR2C (0.43) | ACACBACACAIDO1SERPINE1 | |
| SCHEMBL17986443 | 0.73 | HTR2C (0.51) | — | |
| SCHEMBL17985452 | 0.73 | HTR2C (0.63) | — | |
| SCHEMBL17986613 | 0.73 | HTR2A (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |