Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119300 | 1.00 | TSHR (0.43) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL819602 | 1.00 | TSHR (0.43) | TSHRTHPOFFAR3LCKFYN | |
| Methane SCHEMBL15247107 | 0.96 | TSHR (0.40) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL105999 | 0.88 | FFAR3 (0.55) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL141678 | 0.88 | FFAR3 (0.55) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL10661655 | 0.88 | FFAR3 (0.55) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL10661623 | 0.88 | FFAR3 (0.55) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL105998 | 0.88 | FFAR3 (0.55) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL11662990 | 0.84 | FFAR3 (0.50) | TSHRTHPOFFAR3LCKFYN | |
| SCHEMBL11662989 | 0.84 | FFAR3 (0.50) | TSHRTHPOFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045108-A | Herbicidal and plant growth-regulating N-aryl-pyrrol-L-one and isoindol-2-one compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0403891-A1 | N-Aryl-nitrogen-heterocyclic compounds | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |