Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 1/20 | 0.64 |
| ▸ | CDK4 | P11802 | 1/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.64 |
| ▸ | CCND1 | P24385 | 1/20 | 0.64 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293378 | 1.00 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8710180 | 0.85 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8710177 | 0.85 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL12379205 | 0.83 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9857489 | 0.83 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9857485 | 0.83 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5992723 | 0.81 | CCNB2 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5992725 | 0.81 | CCNB2 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8703525 | 0.80 | CCNB2 (0.59) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8703521 | 0.80 | CCNB2 (0.59) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |