Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.66 |
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.66 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.66 |
| ▸ | CCND1 | P24385 | 1/20 | 0.66 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.66 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710177 | 1.00 | CCNB2 (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8522682 | 0.87 | PTGER4 (0.58) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8522681 | 0.87 | PTGER4 (0.58) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6183746 | 0.87 | CCNB2 (0.55) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6183753 | 0.87 | CCNB2 (0.55) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9857485 | 0.85 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL12379205 | 0.85 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7293378 | 0.85 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9871990 | 0.85 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL9857489 | 0.85 | CCNB2 (0.64) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |