Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22808210 | 0.87 | SMN1; SMN2 (0.63) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7321919 | 0.84 | EGFR (0.57) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL27943694 | 0.84 | MGLL (0.56) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL8328458 | 0.82 | MEN1 (0.64) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL3038608 | 0.82 | MGLL (0.58) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL5864056 | 0.82 | MGLL (0.52) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL14183670 | 0.81 | POLB (0.67) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL11694836 | 0.81 | TP53 (0.57) | MGLLTP53MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9872943 | 0.80 | POLB (0.71) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7595080 | 0.79 | MGLL (0.49) | MGLLTP53MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017582-A | Analgesics | SANDOZ LTD. (CH) | 1991-05-21 | — | — | US | disclosed |
| US-4910207-A | Antipsychotic agent | NOVARTIS AG (CH) | 1990-03-20 | — | — | US | disclosed |
| US-4803199-A | SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS | NOVARTIS AG (CH) | 1989-02-07 | — | — | US | disclosed |