Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108473 | 0.98 | CYP4F2 (0.41) | CYP4F2CYP4A11FFAR1TDP1CPT2 | |
| SCHEMBL8037881 | 0.87 | FFAR1 (0.40) | CYP4F2CYP4A11FFAR1TDP1CPT2 | |
| SCHEMBL11166753 | 0.85 | GPR84 (0.45) | FFAR1TDP1GPR84FFAR4ALDH1A1 | |
| SCHEMBL11161811 | 0.85 | GPR84 (0.45) | FFAR1TDP1GPR84FFAR4ALDH1A1 | |
| SCHEMBL28727393 | 0.83 | GPR84 (0.44) | FFAR1TDP1GPR84FFAR4ALDH1A1 | |
| SCHEMBL9870687 | 0.83 | FFAR1 (0.38) | CYP4F2CYP4A11FFAR1TDP1CPT2 | |
| SCHEMBL28727677 | 0.83 | GPR84 (0.44) | FFAR1TDP1GPR84FFAR4ALDH1A1 | |
| SCHEMBL28727659 | 0.83 | GPR84 (0.44) | FFAR1TDP1GPR84FFAR4ALDH1A1 | |
| SCHEMBL28729115 | 0.83 | GPR84 (0.44) | FFAR1TDP1GPR84FFAR4ALDH1A1 | |
| SCHEMBL11109837 | 0.83 | FFAR1 (0.35) | FFAR1TDP1CPT2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997847-A | Thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0304271-A2 | Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-22 | — | — | EP | disclosed |