Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874266 | 0.88 | TSHR (0.53) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL5023249 | 0.87 | TSHR (0.55) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL7720528 | 0.81 | PDPK1 (0.65) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL4340900 | 0.80 | PDPK1 (0.61) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL4345266 | 0.80 | PDPK1 (0.61) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL5830234 | 0.78 | PDPK1 (0.65) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL13109573 | 0.78 | PDPK1 (0.65) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL9873991 | 0.77 | PDPK1 (0.46) | PDPK1MTORTSHRALDH1A1 | |
| SCHEMBL13109619 | 0.77 | PDPK1 (0.68) | PDPK1MTORTSHRFUCA1CETP | |
| SCHEMBL9874053 | 0.77 | PDPK1 (0.63) | PDPK1MTORTSHRFUCA1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055597-A | SYNTHESIS OF INOSITOL PHOSPHATES | MERCK SHARP & DOHME LTD. (GB) | 1991-10-08 | — | — | US | disclosed |
| US-4906761-A | Myo-inositol orthoformates | MERCK SHARPE & DOHME LTD. (GB) | 1990-03-06 | — | — | US | disclosed |