Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | IGF1R | P08069 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21637212 | 0.78 | MAPT (0.41) | MAPTGAANPC1HTTLMNA | |
| SCHEMBL18007670 | 0.77 | MAPT (0.44) | MAPTGAANPC1HTTLMNA | |
| SCHEMBL949243 | 0.77 | GAA (0.45) | AGTR1MAPTGAANPC1LMNA | |
| SCHEMBL8820141 | 0.76 | IGF1R (0.43) | MAPTGAAIGF1RPKM | |
| SCHEMBL13033010 | 0.75 | MAPK1 (0.65) | GAAHRH4POLBPKM | |
| Cyprodinil SCHEMBL22669 | 0.75 | TAAR1 (0.55) | MAPTGAAIGF1RNPC1HTT | |
| SCHEMBL8817791 | 0.75 | HRH4 (0.50) | HRH4SMN1; SMN2 | |
| SCHEMBL18029725 | 0.74 | LRRK2 (0.33) | MAPTHRH4NPC1HTTPOLB | |
| SCHEMBL31453549 | 0.74 | TLR8 (0.47) | MAPTGAALMNA | |
| SCHEMBL24288000 | 0.74 | ALDH1A1 (0.38) | GAAIGF1RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010082-A | Fungicides, microbiocides | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0362135-A2 | Parasiticide | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |