Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064518 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL10932816 | 0.82 | PPARG (0.49) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL276584 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL18473589 | 0.80 | PPARG (0.55) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL9344432 | 0.80 | LMNA (0.49) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL5507885 | 0.80 | PTPN7 (0.56) | CYP1A2CYP2A6PPARGPPARARAB9A | |
| SCHEMBL21131316 | 0.79 | PPARG (0.47) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL27859800 | 0.78 | CYP2A6 (0.46) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL3997055 | 0.78 | AGXT (0.46) | CYP1A2CYP2A6PPARGPPARAAGXT | |
| SCHEMBL9493659 | 0.78 | PPARG (0.46) | CYP1A2CYP2A6PPARGPPARAAGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |