Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872444 | 0.81 | KCNN4 (0.48) | KCNN4 | |
| SCHEMBL2816468 | 0.81 | ALDH1A1 (0.39) | KCNN4TAAR1KDM4EMAPTKMT2A | |
| SCHEMBL198144 | 0.77 | KCNN4 (0.32) | KCNN4ALDH1A1 | |
| SCHEMBL1820792 | 0.75 | KDM4E (0.30) | KDM4EMAPTKMT2A | |
| Benzene SCHEMBL4593432 | 0.74 | TSHR (0.38) | MAPTALDH1A1CYP1A2 | |
| Biphenyl SCHEMBL9539322 | 0.73 | ALDH1A1 (0.33) | KCNN4KMT2AMAPK1ALDH1A1AKT1 | |
| SCHEMBL1516243 | 0.72 | — | — | |
| SCHEMBL209178 | 0.71 | KCNN4 (0.58) | KCNN4TAAR1SLC6A2MAPTKMT2A | |
| SCHEMBL7492959 | 0.70 | SLC6A2 (0.41) | TAAR1SLC6A2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8115695 | 0.69 | KDM4E (0.35) | KCNN4KDM4EKMT2AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |