Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270078 | 0.91 | ALDH1A1 (0.48) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| Hydrochloric Acid SCHEMBL9871841 | 0.86 | HTT (0.49) | ALDH1A1MAPTPTGDR2GAACYP1A2 | |
| Hydrochloric Acid SCHEMBL7270360 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| Cadaverine Tartrate SCHEMBL9870481 | 0.83 | CYP1A2 (0.46) | ALDH1A1MAPTPOLBPTGDR2GAA | |
| Hydrochloric Acid SCHEMBL7270544 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBGAACYP1A2 | |
| Cadaverine Tartrate SCHEMBL7275463 | 0.79 | CYP1A2 (0.44) | ALDH1A1MAPTPOLBPTGDR2GAA | |
| SCHEMBL10373669 | 0.74 | HCRTR1 (0.38) | — | |
| SCHEMBL10530713 | 0.74 | CYP11B1 (0.42) | — | |
| SCHEMBL1302257 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBPTGDR2GAA | |
| SCHEMBL9872440 | 0.74 | PARP1 (0.52) | ALDH1A1MAPTPOLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071864-A | Administering for high blood pressure and central nervous syst em disorders | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |