Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161697 | 0.85 | GRIN2B (0.76) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL7473599 | 0.83 | POLB (0.53) | GRIN2BALDH1A1MAPTHTR7CYP2C9 | |
| SCHEMBL13648726 | 0.82 | L3MBTL3 (0.72) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL13648728 | 0.82 | L3MBTL3 (0.72) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL8584491 | 0.80 | L3MBTL3 (0.70) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL22848095 | 0.80 | L3MBTL3 (0.70) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL22848097 | 0.80 | L3MBTL3 (0.70) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| Hydrochloric Acid SCHEMBL8814411 | 0.79 | L3MBTL3 (0.68) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL12662876 | 0.79 | L3MBTL3 (0.73) | GRIN2BL3MBTL1MBTD1L3MBTL3GAA | |
| SCHEMBL14768684 | 0.78 | KDM4E (0.51) | GRIN2BALDH1A1KDM4ECYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |