Toluene

Toluene

SCHEMBL9872477

Cc1ccccc1.[Al+3].[H-].[H-].[H-]

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL29091377 0.96
Toluene SCHEMBL25279043 0.96
Toluene SCHEMBL14954017 0.92
Toluene SCHEMBL9806869 0.92
Toluene SCHEMBL11672967 0.92 ACHE (0.85)
Toluene SCHEMBL3410328 0.92 ACHE (0.85)
Toluene SCHEMBL8546810 0.92
Toluene SCHEMBL14954361 0.92
Toluene SCHEMBL4429042 0.92 ACHE (1.00)
SCHEMBL12344943 0.92 ACHE (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108794519-B A kind of oxygen bridge containing boric acid deriveding group is bicyclic-[2.2.1]-heptan vinyl compound, its synthetic method and application 武汉大学 2019-11-08 CN disclosed
CN-108794519-A A kind of oxygen bridge containing boric acid deriveding group is bicyclic-[2.2.1]-heptan vinyl compound, its synthetic method and application 武汉大学 2018-11-13 CN disclosed
CN-104981460-B Synthesis of N-heterocyclic carbenes and intermediates thereof 圣安德鲁斯大学董事会 2018-01-23 CN disclosed
CN-107253903-A Prepare a kind of method that can combine S1P acceptor compounds and its intermediate 北京海步医药科技股份有限公司 2017-10-17 CN disclosed
CN-107001346-A The base of 1 oxo, 1,2 dihydro-isoquinoline 7 bases of thiophene 2 of substitution (5) sulfonamide compounds, the preparation for containing those compounds and their purposes as AICARFT inhibitor in treating cancer 伊莱利利公司 2017-08-01 CN disclosed
CN-106458887-A novel pyrrolidine compounds and their use as melanocortin receptor agonists 田边三菱制药株式会社 2017-02-22 CN disclosed
US-5001255-A Idene analogs of mevalonolactone and derivatives thereof SANDOZ PHARM. CORP. (US) 1991-03-19 US disclosed