Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027818 | 1.00 | CYP1A2 (0.53) | CYP1A2SLC9A1TLR8PNPMEN1 | |
| SCHEMBL9871920 | 1.00 | CYP1A2 (0.53) | CYP1A2SLC9A1TLR8PNPMEN1 | |
| SCHEMBL9872320 | 1.00 | CYP1A2 (0.53) | CYP1A2SLC9A1TLR8PNPMEN1 | |
| SCHEMBL544848 | 0.98 | CYP1A2 (0.55) | CYP1A2SLC9A1TLR8MEN1KMT2A | |
| SCHEMBL18496466 | 0.92 | CYP1A2 (0.57) | CYP1A2SLC9A1MEN1KMT2AHTT | |
| SCHEMBL21270136 | 0.87 | CYP1A2 (0.67) | CYP1A2MEN1KMT2AHTT | |
| SCHEMBL15323890 | 0.83 | — | — | |
| SCHEMBL21270138 | 0.83 | CYP1A2 (0.67) | CYP1A2MEN1KMT2AHTT | |
| SCHEMBL2092215 | 0.80 | SLC9A1 (0.45) | CYP1A2SLC9A1MEN1KMT2AHTT | |
| SCHEMBL948403 | 0.78 | SLC9A1 (0.44) | SLC9A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |