Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962480 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TRPV1KMT2AMEN1KDR | |
| SCHEMBL9872140 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TRPV1KMT2AMEN1KDR | |
| SCHEMBL9872505 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TRPV1KMT2AMEN1KDR | |
| SCHEMBL22205130 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TRPV1 | |
| SCHEMBL22205164 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TRPV1 | |
| SCHEMBL22205113 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TRPV1 | |
| SCHEMBL22205184 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TRPV1 | |
| SCHEMBL22205140 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TRPV1 | |
| SCHEMBL4413802 | 0.78 | TRPV1 (0.43) | TRPV1KMT2A | |
| SCHEMBL4404362 | 0.78 | TRPV1 (0.43) | TRPV1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073565-A | Atherosclerosis, anticholesterol | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| WO-1991017150-A1 | TETRAZOLE UREA AND THIOUREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-11-14 | — | — | WO | disclosed |