Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 7/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873247 | 0.97 | CYP2J2 (0.63) | CYP2J2HRH1NPY2RPAX8KCNH2 | |
| SCHEMBL9872613 | 0.93 | CYP2J2 (0.61) | CYP2J2HRH1NPY2RPAX8MEN1 | |
| SCHEMBL9873058 | 0.87 | CYP2J2 (0.65) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9874649 | 0.86 | CYP2J2 (0.54) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873405 | 0.86 | CYP2J2 (0.54) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9872567 | 0.86 | CYP2J2 (0.67) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9873120 | 0.84 | CYP2J2 (0.67) | CYP2J2HRH1NPY2RPAX8KCNH2 | |
| SCHEMBL9873919 | 0.84 | CYP2J2 (0.61) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9874017 | 0.83 | CYP2J2 (0.51) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 | |
| SCHEMBL9874087 | 0.83 | CYP2J2 (0.51) | CYP2J2HRH1KCNH2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |