Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 10/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874087 | 0.97 | CYP2J2 (0.51) | CYP2J2CYP2C9CYP3A4CYP2B6MEN1 | |
| SCHEMBL9873346 | 0.93 | GAA (0.52) | CYP2J2CYP2C9MEN1KMT2ANPSR1 | |
| SCHEMBL9873058 | 0.89 | CYP2J2 (0.65) | CYP2J2CYP2C9CYP3A4CYP2B6NPSR1 | |
| SCHEMBL9874649 | 0.88 | CYP2J2 (0.54) | CYP2J2CYP2C9CYP3A4CYP2B6MEN1 | |
| SCHEMBL9872567 | 0.88 | CYP2J2 (0.67) | CYP2J2CYP2C9CYP3A4CYP2B6NPSR1 | |
| SCHEMBL9872734 | 0.86 | CYP2J2 (0.67) | CYP2J2CYP2C9CYP3A4CYP2B6MEN1 | |
| SCHEMBL9873919 | 0.86 | CYP2J2 (0.61) | CYP2J2CYP2C9CYP3A4CYP2B6NPSR1 | |
| SCHEMBL9874097 | 0.85 | CYP2J2 (0.49) | CYP2J2CYP2C9CYP3A4CYP2B6MEN1 | |
| SCHEMBL9874017 | 0.85 | CYP2J2 (0.51) | CYP2J2CYP2C9CYP3A4CYP2B6HRH1 | |
| SCHEMBL9872364 | 0.85 | CYP2J2 (0.62) | CYP2J2CYP2C9CYP3A4CYP2B6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057524-A | Asthma, dermatitis | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |