Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249565 | 0.79 | TSHR (0.44) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL23249568 | 0.79 | TSHR (0.44) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL29864729 | 0.79 | TSHR (0.44) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL6257249 | 0.77 | ALDH1A1 (0.48) | TSHRALDH1A1 | |
| SCHEMBL16198017 | 0.76 | TSHR (0.58) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL575530 | 0.76 | ALDH1A1 (0.65) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL987906 | 0.76 | TSHR (0.65) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL10515464 | 0.76 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2166794 | 0.74 | TSHR (0.39) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL2166791 | 0.74 | TSHR (0.39) | TSHRALDH1A1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023361-A | Process for preparing hydroxyalkylating agents, the agents so obtained, and their use | RHONE-POULENC SANTE (FR) | 1991-06-11 | — | — | US | disclosed |