Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 18/20 | 1.00 |
| ▸ | DRD2 | P14416 | 17/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.78 |
| ▸ | DRD4 | P21917 | 2/20 | 0.78 |
| ▸ | DRD5 | P21918 | 2/20 | 0.78 |
| ▸ | HTR2A | P28223 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203039 | 0.81 | DRD2 (1.00) | DRD1DRD2DRD4 | |
| SCHEMBL22077139 | 0.80 | DRD2 (0.69) | DRD1DRD2ADRA2ADRD4DRD5 | |
| SCHEMBL20369209 | 0.78 | DRD2 (0.77) | DRD1DRD2ADRA2ADRD4DRD5 | |
| SCHEMBL14133772 | 0.78 | DRD2 (0.91) | DRD1DRD2DRD4 | |
| SCHEMBL11925297 | 0.78 | DRD2 (0.75) | DRD1DRD2DRD4 | |
| SCHEMBL22147037 | 0.77 | DRD2 (0.65) | DRD1DRD2ADRA2ADRD4DRD5 | |
| SCHEMBL14133020 | 0.76 | DRD2 (0.88) | DRD1DRD2ADRA2ADRD4DRD5 | |
| SCHEMBL20751643 | 0.76 | DRD2 (0.67) | DRD1DRD2ADRA2ADRD4DRD5 | |
| SCHEMBL14052668 | 0.76 | DRD2 (0.91) | DRD1DRD2DRD4 | |
| SCHEMBL20751654 | 0.76 | DRD2 (0.69) | DRD1DRD2ADRA2ADRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010661-A1 | DERIVATIVES OF 5-AMINO-8-CHLORINE-DIBENZO[b,e][1,4]-DIAZEPINE AND A PHARMACEUTICAL PREPARATION FOR TREATMENT OF EPILEPSY AND EPILEPTIC STATUS BASED THEREON | NOVOKUZNETSKY NAUCHNO-ISSLEDOVATELSKY KHIMIKO-FARMATSEVTICHESKY INSTITUT (SU) | 1991-07-25 | — | — | WO | disclosed |