Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872980 | 0.81 | TDP1 (0.56) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL9872931 | 0.71 | CYP3A4 (0.48) | KARS1TDP1CYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9871425 | 0.70 | CYP3A4 (0.49) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL9872658 | 0.69 | CYP3A4 (0.39) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL9745072 | 0.69 | CYP3A4 (0.57) | KARS1TDP1CYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9870784 | 0.69 | CYP3A4 (0.40) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL19696490 | 0.68 | KARS1 (0.53) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL19696488 | 0.67 | KARS1 (0.54) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL19018793 | 0.66 | CYP3A4 (0.57) | KARS1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL20866213 | 0.66 | CYP3A4 (0.57) | KARS1TDP1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039706-A | Antiinflammatory, antiallergenic agent | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-13 | — | — | US | disclosed |