Helicin

Helicin

SCHEMBL987304

O=Cc1ccccc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 6/20 0.57
SLC28A3 Q9HAS3 2/20 0.56
SLC5A1 P13866 2/20 0.55
ATM Q13315 1/20 0.54
TYR P14679 2/20 0.52
HIF1A Q16665 1/20 0.52
PTPN1 P18031 1/20 0.49
EPHX2 P34913 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Helicin SCHEMBL9844557 1.00 SLC5A2 (0.57) SLC5A2SLC28A3SLC5A1ATMTYR
Helicin SCHEMBL20723406 1.00 SLC5A2 (0.57) SLC5A2SLC28A3SLC5A1ATMTYR
Helicin SCHEMBL9844555 1.00 SLC5A2 (0.57) SLC5A2SLC28A3SLC5A1ATMTYR
Helicin SCHEMBL988045 1.00 SLC5A2 (0.57) SLC5A2SLC28A3SLC5A1ATMTYR
Helicin SCHEMBL1006709 1.00 SLC5A2 (0.57) SLC5A2SLC28A3SLC5A1ATMTYR
Helicin SCHEMBL9888348 1.00 SLC5A2 (0.57) SLC5A2SLC28A3SLC5A1ATMTYR
SCHEMBL31064785 0.99 SLC28A3 (0.55) SLC5A2SLC28A3SLC5A1ATMTYR
Helicin SCHEMBL18864319 0.93 SLC5A2 (0.54) SLC5A2SLC28A3SLC5A1ATMTYR
SCHEMBL14120353 0.86 HIF1A (0.54) SLC5A2SLC28A3SLC5A1ATMTYR
SCHEMBL16874167 0.86 ATM (0.54) SLC5A2SLC28A3SLC5A1ATMTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025095174-A1 DEEP-FRIED AND BRAISED CHICKEN SAUCE WITH IMPROVED COLOR AND TEXTURE AND DEEP-FRIED AND BRAISED CHICKEN PREPARED BY USING SAME 지병욱 2025-05-08 WO claimed
US-12285488-B2 Oral dosage form containing theobromine-free cocoa LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2025-04-29 US claimed
WO-2025073376-A1 MASKING PREPARATIONS AND COMPOUNDS FROM DAEMONOROPS DRACO (DRAGON BLOOD) SYMRISE AG (DE) 2025-04-10 WO claimed
US-20240050458-A1 Compositions And Methods For Inducing Apopotosis In Anaerobic Cells And Related Clinical Methods For Treating Cancer And Pathogenic Infections ROBERTS SUZANNAH JANE (US) 2024-02-15 US claimed
US-20200253998-A1 Compositions And Methods For Immunotherapy BROWN JOE ERNEST (US) 2020-08-13 US claimed
EP-3665180-A1 COMPOSITIONS AND METHODS FOR INDUCING APOPTOSIS IN ANAEROBIC CELLS AND RELATED CLINICAL METHODS FOR TREATING CANCER AND PATHOGENIC INFECTIONS Cognate 3 LLC (US) 2020-06-17 EP claimed
WO-2019032411-A1 COMPOSITIONS AND METHODS FOR INDUCING APOPTOSIS IN ANAEROBIC CELLS AND RELATED CLINICAL METHODS FOR TREATING CANCER AND PATHOGENIC INFECTIONS COGNATE 3 LLC (US) 2019-02-14 WO claimed
US-20160113955-A1 Compositions And Methods For Immunotherapy BROWN JOE ERNEST (US) 2016-04-28 US claimed
US-20160008388-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY BROWN JOE ERNEST (US) 2016-01-14 US claimed
US-20120251490-A1 Compositions And Methods For Immunotherapy BROWN JOE ERNEST (US) 2012-10-04 US claimed
WO-2009145841-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY COGNATE 3, LLC (US) 2009-12-03 WO claimed
EP-1337229-B1 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL AG & CO KGAA (DE) 2009-09-30 EP claimed
US-20060248602-A1 Bitter taste receptors DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG (DE) 2006-11-02 US claimed
EP-1543122-A2 BITTER TASTE RECEPTORS Deutsches Institut für Ernährungsforschung (DE) 2005-06-22 EP claimed
WO-2004029087-A2 BITTER TASTE RECEPTORS Deutsches Institut für Ernährungsforschung (DE) 2004-04-08 WO claimed
EP-0992277-B1 Dry semipermeable reverse osmosis membrane and process for preparing the same using saccharides SAEHAN IND INC (KR) 2004-04-07 EP claimed
EP-1337229-A2 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-08-27 EP claimed
WO-2002043675-A2 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-06 WO claimed
EP-0992277-A1 Dry semipermeable reverse osmosis membrane and process for preparing the same using saccharides SAEHAN INDUSTRIES, INC. (KR) 2000-04-12 EP claimed
US-4255319-A PHOSPHINE INHIBITION; NONTOXIC; STORAGE STABILITY; MATERIALS HANDLING UNION CARBIDE CORPORATION (US) 1981-03-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160008388-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY ICOS, IL2, NFATC1 SLC5A2 3415/4885SLC28A3 4445/4885SLC5A1 3626/4885
US-20240050458-A1 Compositions And Methods For Inducing Apopotosis In Anaerobic Cells And Related Clinical Methods For Treating Cancer And Pathogenic Infections ENGASE, AGL, GAA SLC5A2 1011/4885SLC28A3 3379/4885SLC5A1 993/4885
US-20120251490-A1 Compositions And Methods For Immunotherapy ICOS, IL2, NFATC1 SLC5A2 3415/4885SLC28A3 4445/4885SLC5A1 3626/4885
US-20060248602-A1 Bitter taste receptors TAS2R1, TAS2R30, TAS2R5 SLC5A2 964/4885SLC28A3 1555/4885SLC5A1 769/4885
US-20200253998-A1 Compositions And Methods For Immunotherapy ICOS, NFATC1, IL2 SLC5A2 3588/4885SLC28A3 4547/4885SLC5A1 3975/4885
US-20160113955-A1 Compositions And Methods For Immunotherapy ICOS, IL2, NFATC1 SLC5A2 3415/4885SLC28A3 4445/4885SLC5A1 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.